Pietro Cottone Selected Research

Alcoholism (Alcohol Abuse)

11/2023	Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) of the Bed Nucleus of the Stria Terminalis Mediates Heavy Alcohol Drinking in Mice.
1/2021	Viral-Mediated Knockdown of Nucleus Accumbens Shell PAC1 Receptor Promotes Excessive Alcohol Drinking in Alcohol-Preferring Rats.
1/2021	Pituitary adenylate cyclase-activating polypeptide (PACAP) modulates dependence-induced alcohol drinking and anxiety-like behavior in male rats.
1/2019	Role of Sigma Receptors in Alcohol Addiction.
1/2017	Sigma Receptors and Alcohol Use Disorders.
1/2015	Sigma-1 receptor mediates acquisition of alcohol drinking and seeking behavior in alcohol-preferring rats.
6/2013	mTOR activation is required for the anti-alcohol effect of ketamine, but not memantine, in alcohol-preferring rats.
5/2011	Activation of σ-receptors induces binge-like drinking in Sardinian alcohol-preferring rats.
5/2010	Corticotropin releasing factor-induced amygdala gamma-aminobutyric Acid release plays a key role in alcohol dependence.
5/2009	The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Pietro Cottone Research Topics

Disease

10	Alcoholism (Alcohol Abuse) 11/2023 - 05/2009
7	Food Addiction 01/2020 - 09/2012
6	Body Weight (Weight, Body) 07/2015 - 10/2013
4	Hyperalgesia 01/2023 - 01/2020
4	Bulimia (Binge Eating) 01/2017 - 09/2012
4	Anorexia 07/2015 - 05/2007
3	Pain (Aches) 01/2023 - 01/2020
3	Substance-Related Disorders (Drug Abuse) 01/2017 - 04/2009
3	Obesity 09/2015 - 09/2007
2	Binge-Eating Disorder (Binge Eating Disorder) 12/2015 - 03/2015
2	Hyperphagia (Overeating) 12/2015 - 11/2009
1	Anxiety Disorders (Anxiety Disorder) 01/2023
1	Chronic Pain 01/2023
1	Wounds and Injuries (Trauma) 09/2022
1	Hypersensitivity (Allergy) 01/2021
1	Memory Disorders (Memory Loss) 05/2020
1	Morphine Dependence 01/2017
1	Anhedonia 10/2015
1	Body Weight Changes 07/2015
1	Binge Drinking 04/2013
1	Weight Gain 09/2012
1	Genetic Predisposition to Disease (Genetic Predisposition) 08/2009
1	Feeding and Eating Disorders (Eating Disorder) 05/2007

Drug/Important Bio-Agent (IBA)

7	Ethanol (Ethyl Alcohol)IBA 01/2021 - 05/2009
6	Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)IBA 11/2023 - 10/2013
4	sigma Receptors (sigma Receptor)IBA 01/2019 - 05/2011
3	Sigma-1 ReceptorIBA 01/2021 - 01/2015
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2016
3	Memantine (Namenda)FDA Link 05/2020 - 06/2013
3	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 05/2020 - 06/2013
3	RimonabantIBA 10/2014 - 11/2013
3	Corticotropin-Releasing HormoneIBA 05/2010 - 09/2007
2	NeuropeptidesIBA 01/2023 - 09/2022
2	1- (2- (3,4- dichlorophenyl)ethyl)- 4- methylpiperazineIBA 01/2021 - 01/2015
2	Peptides (Polypeptides)IBA 12/2015 - 07/2015
2	Appetite Depressants (Anorectics)IBA 09/2015 - 09/2007
2	CannabinoidsIBA 09/2014 - 11/2013
2	Naltrexone (ReVia)FDA LinkGeneric 07/2014 - 04/2013
1	Designer DrugsIBA 01/2023
1	LigandsIBA 01/2021
1	ElementsIBA 01/2021
1	sigma-2 receptorIBA 01/2021
1	Dopamine (Intropin)FDA LinkGeneric 01/2020
1	Trace amine-associated receptor 1IBA 01/2018
1	EndocannabinoidsIBA 01/2017
1	Messenger RNA (mRNA)IBA 01/2017
1	Opioid Analgesics (Opioids)IBA 12/2015
1	SaccharinIBA 10/2015
1	Dopamine Agonists (Dopamine Agonist)IBA 09/2015
1	Dopamine Receptors (Dopamine Receptor)IBA 09/2015
1	Dextroamphetamine (Dexedrine)FDA LinkGeneric 09/2015
1	MelanocortinsIBA 07/2015
1	SHU 9119IBA 07/2015
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 07/2015
1	Adenylyl Cyclases (Adenylyl Cyclase)IBA 07/2015
1	Type 3 Melanocortin ReceptorIBA 07/2015
1	Corticotropin-Releasing Hormone Receptors (Corticotropin Releasing-Hormone Receptor)IBA 07/2015
1	staurosporine aglycone (K252a)IBA 07/2015
1	N-Methylaspartate (NMDA)IBA 03/2015
1	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 09/2014
1	Transcription Factors (Transcription Factor)IBA 09/2014
1	CorticosteroneIBA 10/2013
1	Sucrose (Saccharose)IBA 09/2012
1	gamma-Aminobutyric Acid (GABA)IBA 05/2010
1	Adrenocorticotropic Hormone (ACTH)FDA Link 11/2009
1	N,N- dipropyl- 2- (4- methoxy- 3- (2- phenylethoxy)phenyl)ethylamine monohydrochlorideIBA 08/2009
1	UrocortinsIBA 09/2007
1	FG 7142IBA 05/2007
1	Flumazenil (Romazicon)FDA LinkGeneric 05/2007
1	GABA-A Receptors (GABA(A) Receptor)IBA 05/2007

Therapy/Procedure

2	Drug Therapy (Chemotherapy) 01/2018 - 01/2017
1	Therapeutics 01/2017
1	Self Medication 09/2012